Table 1.
Normal range (SI units) | Normal range (Conventional units) | |
---|---|---|
Serum calcium | 2.2–2.6 mMol/L | 8.8–10.4 mg/dL |
Ionized calciuma | 1.1–1.3 mMol/L | 4.4–5.2 mg/dL |
PTH | 1.6–6.9 pMol/L | 15–65 pg/mL |
Calcidiol, or 25-hydroxyvitamin D [25(OH)D]b | 50–200 nMol/L | 20–80 ng/mL |
PTH: parathyroid hormone; SI: International System.
Albeit all calcium in the body is technically ionized, the term usually only applies to the free ionic fraction that is physiologically active in the blood.
In contrast to 25(OH)D, circulating calcitriol, also known as 1,25(OH)2D, is generally not a good indicator of vitamin D status because it has a short half-life of 15 hours and serum concentrations are closely regulated by parathyroid hormone, calcium, and phosphate; levels of 1,25(OH)2D do not typically decrease until vitamin D deficiency is severe.