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. 2020 Jun 2;13:4919–4929. doi: 10.2147/OTT.S238808

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© 2020 Jiang et al.

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XIST deletion inhibits cell proliferation, migration and invasion but induces cell apoptosis in NSCLC. XIST was silenced using siRNA sequences targeting XIST in A549 and H1299 cells. (A and B) The efficiencies of interference were detected using qRT-PCR. (C and D) CCK-8 assay was used to measure cell proliferation. (E and F) Apoptotic cells were examined by flow cytometry. (G and H) Migrated and invaded cells were examined using transwell assay. *P<0.05.