Figure 2. Associations of CD4+ T helper cell subsets specified as primary hypotheses with incident myocardial infarction or incident angina.
Cell subsets were analyzed per 1-SD higher values using Cox proportional hazards models with sampling weights. Confidence intervals (CIs) used robust (sandwich) standard error estimates and reflect the Bonferroni-adjusted significance level of p<0.0071. Th1, Th2, and Th17 cells were not meta-analyzed due to differences in phenotyping (as described in the Methods). Models were adjusted for age, sex, race/ethnicity, education, clinical site, systolic blood pressure, use of antihypertensive medications, low-density lipoprotein cholesterol, use of statins, smoking, and diabetes.