TABLE 1.

Physiological variables of eight healthy beagle dogs undergoing colloid fluid infusion for 120 min with 10 mL/kg/h of Gelofusine^® (succinylated gelatin) or Voluven^® (tetrastarch 130/0.4).

Parameter	Treat	0			15			30			45			60			75			90			105			120
		Mean	Min	Max	Mean	Min	Max	Mean	Min	Max	Mean	Min	Max	Mean	Min	Max	Mean	Min	Max	Mean	Min	Max	Mean	Min	Max	Mean	Min	Max
HR (bepm)	GEL	79	50	122	91	73	109	90	73	108	89	67	102	91	66	105	90	65	104	92	69	106	94	68	102	94	68	112
	VOL	84	55	103	90	65	109	94	68	109	96	77	109	96	77	107	97	85	107	95	75	105	94	75	107	93	73	105
SAP (mmHg)	GEL	118	98	132	105	80	125	103	90	123	108	93	120	109	97	127	110	92	122	116	92	128	118	97	129	118	90	105
	VOL	120	85	156	116	85	141	116	78	158	113	78	147	113	81	147	112	88	157	111	87	155	115	90	152	111	83	148
MAP (mmHg)	GEL	90	72	110	81	68	98	78	68	89	82	71	94	81	67	94	83	75	94	83	75	94	83	74	94	85	75	94
	VOL	89	70	130	87	70	129	84	68	126	83	70	119	82	69	124	80	64	122	79	67	120	80	65	120	79	64	119
DAP (mmHg)	GEL	74	52	102	67	53	93	67	53	78	68	56	81	67	56	80	69	59	80	67	59	79	68	59	79	70	59	82
	VOL	75	59	111	72	57	117	70	54	110	69	55	107	68	55	109	65	52	105	66	50	104	64	49	103	65	49	103
PP (mmHg)	GEL	44	26	54	35	11	50	36	16	55	39	20	61	42	25	59	42	24	60	49	24	60	48	34	62	48	21	74
	VOL	45	21	66	44	23	65	46	18	65	43	15	69	45	16	74	46	27	68	45	26	67	51	35	70	47	29	62
Temp (°C)	GEL	36.2	35.0	36.9	36.1	35.4	36.9	36.0	34.8	37.2	36.0	35.0	37.4	36.3	35.2	37.5	36.5	35.5	37.6	36.7	35.8	37.8	36.8	36.0	37.7	36.9	36.1	37.8
	VOL	36.2	34.8	37.0	36.0	34.6	36.9	35.9	34.6	36.8	35.9	34.6	37.1	35.9	34.6	37.2	36.0	34.6	37.1	36.0	34.5	37.4	36.0	34.6	37.4	36.1	34.6	37.4
fR (brpm)	GEL	8	5	14	9	4	19	10	5	15	10	6	16	11	6	15	13*	6	24	17*	6	36	18*	6	38	17*	9	32
	VOL	10	7	16	11	7	18	11	7	17	11	6	14	11	8	15	11	8	15	13	8	21	12	7	19	12	8	15
PE’CO2 (mmHg)	GEL	48	46	53	49	45	56	49	45	54	47	36	57	49	44	57	49	43	60	48	43	63	47	43	59	46	42	54
	VOL	49	44	59	49	44	63	50	43	60	50	44	58	49	43	57	51	43	58	50	43	59	49	44	58	49	44	56
SpO2 (%)	GEL	98	93	100	99	96	100	99	95	100	98	95	100	98	95	100	98	94	100	98	95	100	99	94	100	99	94	100
	VOL	100	98	100	99	93	100	99	95	100	99	94	100	99	94	100	99	95	100	99	95	100	99	96	100	99	98	100
FE’iso (%)	GEL	1.3	0.9	1.6	1.4	1.1	1.6	1.3	1.1	1.6	1.4	1.1	1.8	1.3	1.2	1.7	1.3	1.2	1.6	1.4	1.2	1.8	1.4	1.2	1.7	1.3	1.2	1.5
	VOL	1.3	1.1	1.5	1.4	1.2	1.6	1.4	1.3	1.5	1.4	1.3	1.5	1.3	1.3	1.4	1.3	1.2	1.4	1.3	1.2	1.5	1.4	1.2	1.5	1.4	1.2	1.5

Treat, treatment; GEL, Gelofusine^®; VOL, Voluven^®; Min, minimum; Max, maximum: HR, heart rate; bepm, beats/minute; SAP, systolic arterial blood pressure; MAP, mean arterial blood pressure; DAP, diastolic arterial blood pressure; PP, pulse pressure; Temp, temperature; fR, respiratory rate; brpm, breaths/minute; PE’CO₂, end tidal carbon dioxide; SpO_2, oxygen-haemoglobin saturation; FE’iso, end tidal isoflurane.

Variables are reported as mean values and range from immediately prior to initiation of infusion (time 0 min) for 120 min of infusion.

^*, p < 0.05 significant finding over time.