Table 2.
Protein alteration in periodontal disease.
| Protein | Authors (Year) |
|---|---|
| Upregulated | |
| Albumin | Wu Y et al. (2009), Ngo LH et al. (2009), Goncalves L da R et al. (2010), Goncalves L da R et al. (2011), Bostanci N et al. (2012), Silva-Boghossian CM et al. (2013), Carneiro LG et al. (2014), Aboodi GM et al. (2016) |
| S100A6 | Haigh BJ et al. (2010) |
| S100A7 | Kido et al. (2012) |
| S100A8; S100A9 | Haigh BJ et al. (2010), Kido et al. (2012), Silva-Boghossian CM et al. (2013), Carneiro LG et al. (2014), Monari et al. (2015), Shin M-S et al. (2018), Marinho MC et al. (2018), |
| S100A11 | Kido et al. (2012) |
| Matrix metalloproteinase 9 | Tsuchida S et al. (2013), Salazar MG et al. (2013), Trindade F et al. (2015), Bostanci N et al. (2018) |
| Immunoglobulins | Goncalves L da R et al. (2010), Goncalves L da R et al. (2011), Marinho MC et al. (2018) |
| Immunoglobulin G | Ngo LH et al. (2009) |
| Immunoglobulin γ 2 chain C region | Wu Y et al. (2009) |
| Immunoglobulin κ chain C region | Bertoldi C et al. (2013), Kerishnan JP et al. (2016) |
| Hemoglobin | Ngo LH et al. (2009), Goncalves L da R et al. (2010), Goncalves L da R et al. (2011) |
| Transferrin | Ngo LH et al. (2009) |
| Lactotransferrin | Mizuno N et al. (2011), Kido et al. (2012), Salazar MG et al. (2013) |
| Azurocidin | Guzman YA et al. (2018), Choi YJ et al. (2011) |
| Keratins | Goncalves L da R et al. (2010), Goncalves L da R et al. (2011), Silva-Boghossian CM et al. (2013) |
| Ceruloplasmin | Kido et al. (2012), Salazar MG et al. (2013) |
| L-plastin | Bostanci N et al. (2009) |
| α-amylase | Wu Y et al. (2009), Goncalves L da R et al. (2010) |
| Neutrophil defensin-1 | Bostanci N et al. (2012), Baliban CR et al. (2012) |
| Haptoglobin | Davis IJ et al. (2016) |
| Apolipoprotein | Ngo LH et al. (2009) |
| Apolipoprotein A-I | Tsuchida S et al. (2012), Silva-Boghossian CM et al. (2013) |
| Rap guanine nucleotide exchange factor | Marinho MC et al. (2018) |
| Hexokinase; legumain | Yang W et al (2017) |
| Carbonic anhydrase-1; elongation factor-1 γ | Baliban CR et al. (2012) |
| Superoxide dismutase 1; dermcidin | Tsuchida S et al. (2012) |
| Vitamin D-binding protein; zinc-α 2 glycoprotein | Wu Y et al. (2009) |
| α1-antitrypsin; haptoglobin; kininogen | Kerishnan JP et al. (2016) |
| Heat shock protein β-1; galectin-7; 14-3-3 | Monari et al. (2015) |
| Caldesmon; heat shock protein 70; STAC | Mizuno N et al. (2011) |
| Actins; histones; annexins | Silva-Boghossian CM et al. (2013) |
| Hemopexin; plasminogen; α-fibrinogen; Apolipoprotein H | Mertens B et al. (2017) |
| Histone 1.4; keratin type II cytoskeletal 6E; cDNA FLJ53910 (keratin type II cytoskeletal 6A) | Bostanci N et al. (2012) |
| Annexin A2; actin cytoplasmic 1; carbonic anhydrase 1 and 2; flavin reductase | Bertoldi C et al. (2013) |
| Salivary β-globin; thioredoxin; collagen α-1, and G-protein coupled receptor 98 | Aboodi GM et al. (2016) |
| Ras-related protein-1; actin-related protein 2/3 complex subunit 5 | Bostanci N et al. (2018) |
| Blood-, cytoskeleton-, immunity-, inflammation- and lipid-related proteins; glycogen phosphorylase, glutathione S-transferase; phosphoglycerate mutase; psoriasin; resistin; A1-antitrypsin; lipocalin; cathelicidin | Kido et al. (2012) |
| Leukotriene A-4 hydrolase; adenylyl cyclase-associated protein 1; catalase; rho GDP-dissociation inhibitor 2; S100-P; neutrophil collagenase; neutrophil defensin; peptidoglycan recognition protein 1 gelsolin; profilin-1; calreticulin; plastin-2; fibrinogen chain; α-2-macroglobulin; complement C3; α-2-HS-glycoprotein | Salazar MG et al. (2013) |
| Downregulated | |
| Cystatin | Goncalves L da R et al. (2010) |
| Cystatin B; cystatin S | Huynh AHS et al. (2014) |
| Cytokeratin | Yang W et al (2017) |
| 14-3-3 sigma | Wu Y et al. (2009), Bertoldi C et al. (2013) |
| 14-3-3 zeta/delta; heat shock protein β-1; triosephosphate isomerase; peroxiredoxin-1; fatty acid–binding protein-epidermal; galectin-7 | Bertoldi C et al. (2013) |
| Actin; myristoylated alanine-rich C-kinase substrate; glutathione S-transferase; cathelicidin | Marinho MC et al. (2018) |
| Lactotransferrin; elongation factor 2; short palate-, lung- and nasal-epithelium carcinoma-associated protein 2 precursor; carbonic anhydrate 6 | Wu Y et al. (2009) |