Table 3.

Stratification analyses for the associations between BMI and risk of ESCC and GC in the Linxian dysplasia population trial cohort.

	ESCC			GC
	Normal (≥18.5 to <24.0)	Underweight (< 18.5)	Overweight or obese (≥24.0)	Normal (≥18.5 to <24.0)	Underweight (< 18.5)	Overweight or obese (≥24.0)
Age at baselinea
<55 years	1.00	1.35(0.81–2.24)	0.67(0.42–1.06)	1.00	1.10(0.76–1.60)	1.08(0.64–1.81)
≥55 years	1.00	1.09(0.59–1.86)	0.72(0.42–1.25)	1.00	0.95(0.69–1.30)	1.04(0.60–1.81)
P for interaction		0.243			0.930
Genderb
Men	1.00	1.13(0.55–2.03)	0.75(0.38–1.46)	1.00	0.72(0.43–1.32)	1.58(0.93–2.69)
Women	1.00	1.30(0.84–2.04)	0.66(0.44–0.99)	1.00	1.12(0.62–2.01)	0.75(0.44–1.28)
P for interaction		0.020			0.047
Smokingc
Former	1.00	1.05(0.58–2.08)	0.57(0.14–2.40)	1.00	0.66(0.15–1.79)	1.35(0.77–2.39)
Current	1.00	1.08(0.42–1.89)	0.78(0.25–2.45)	1.00	0.82(0.55–1.23)	1.19(0.72–1.97)
Never	1.00	1.27(0.85–1.94)	0.69(0.47–1.01)	1.00	0.83(0.61–1.15)	0.96(0.61–1.49)
P for interaction		0.545			0.235
Drinkingd
Yes	1.00	1.04(0.42–2.60)	0.83(0.36–1.91)	1.00	0.81(0.46–1.40)	0.88(0.35–2.19)
No	1.00	1.28(0.83–1.94)	0.65(0.34–1.05)	1.00	0.93(0.58–1.51)	1.12(0.74–1.69)
P for interaction		0.810			0.668
Family history of cancere
Yes	1.00	1.09(0.83–1.44)	0.58(0.35–0.99)	1.00	0.98(0.68–1.43)	1.10(0.63–1.91)
No	1.00	1.25(0.78–2.01)	0.76(0.48–1.22)	1.00	0.75(0.55–1.68)	1.03(0.62–1.73)
P for interaction		0.003			0.992

Bold text indicates statistical significance. BMI, body mass index. ESCC, Esophageal squamous cell carcinoma. GC, Gastric cancer, including gastric non-cardia carcinoma (GNCC) and cardia carcinoma (GCC).

^aAdjusted for gender, smoking, drinking, family history of cancer, education and consumption of fresh fruit.

^bAdjusted for age at baseline, smoking, drinking, family history of cancer, education and consumption of fresh fruit.

^cAdjusted for age at baseline, gender, drinking, family history of cancer, education and consumption of fresh fruit.

^dAdjusted for age at baseline, gender, smoking, family history of cancer, education and consumption of fresh fruit.

^eAdjusted for age at baseline, gender, smoking, drinking, education and consumption of fresh fruit.