Figure 4. Coexpression network analysis of molecular profile changes after tendon injury.

(A) Hierarchical cluster tree showing distinct modules of co-expressed genes. Modules correspond to branches and are labeled by colors underneath the tree. (B) Correlation matrix of the module eigengene (ME) and time point after tendon injury. Columns correspond to modules and rows correspond to time points (red denotes positive correlation; blue denotes negative correlation). Within each cell, upper value represents the correlation coefficient; lower value represents the corresponding P value. (C) Hierarchical cluster of 13 modules. All the modules are clustered into four classes showing in different colors. (D) Expression trajectory of 13 modules based on ME (first principal component of gene expression).