Table 1.
Patient characteristics
| IIIA (N = 321) | IIIB (N = 262) | IIIA + IIIB (N = 583) | ||
|---|---|---|---|---|
| Characteristic | P * | |||
| N (%) | N (%) | N (%) | ||
| Age | ||||
| < 65 years | 155 (48.3) | 117 (44.7) | 272 (46.7) | |
| ≥ 65 years | 166 (51.7) | 145 (55.3) | 311 (53.3) | |
| Mean ± SD (years) | 64.8 ± 10.5 | 65.1 ± 10.1 | 64.9 ± 10.3 | 0.429 |
| Median (years) | 65.4 | 66.0 | 65.6 | |
| Gender | ||||
| Female | 92 (28.7) | 96 (37.0) | 188 (32.2) | |
| Male | 229 (71.3) | 166 (63.6) | 395 (67.8) | 0.050 |
| Smoking status | ||||
| Current smoker | 161 (50.2) | 147 (56.3) | 308 (52.8) | |
| Former smoker | 127 (39.6) | 92 (35.2) | 219 (37.6) | |
| Never smoker | 26 (8.1) | 16 (6.1) | 42 (7.2) | |
| Unknown | 7 (2.2) | 7 (2.7) | 14 (2.4) | 0.446 |
| Weight loss ≥10% within prior three months | ||||
| No | 243 (75.7) | 163 (62.5) | 406 (69.6) | |
| Yes | 50 (15.6) | 70 (26.8) | 120 (20.6) | |
| Unknown | 28 (8.7) | 29 (11.0) | 57 (9.8) | <0.001 |
| WHO performance status | ||||
| 0 | 86 (26.8) | 60 (23.0) | 146 (25.0) | |
| 1 | 194 (60.4) | 144 (54.9) | 338 (58.0) | |
| 2 | 31 (9.7) | 41 (15.7) | 72 (12.3) | |
| 3 | 10 (3.1) | 17 (6.5) | 27 (4.6) | 0.025 |
| Histology | ||||
| Squamous cell carcinoma | 176 (54.8) | 133 (51.0) | 309 (53.0) | |
| Adenocarcinoma | 115 (35.8) | 105 (40.0) | 220 (37.7) | |
| NSCLC NOS | 18 (5.6) | 18 (6.9) | 36 (6.2) | |
| Other | 12 (3.7) | 6 (2.3) | 18 (3.1) | 0.477 |
* = Chi-square test for IIIA vs. IIIB; NOS = not otherwise specified; NSCLC = non-small-cell lung cancer; SD = standard deviation