Table 3.
Multivariate analysis for PFS and OS
| Covariate | PFS |
OS |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Regional LN involvement∗ | 4.63 | 1.51-14.1 | .007 | 3.09 | 0.87-11.0 | .082 |
| Histology SCC | 0.65 | 0.14-3.07 | .59 | 1.10 | 0.12-8.12 | 1.00 |
| Tumor size >5 cm | 1.03 | 0.34-3.11 | .96 | 1.03 | 0.30-3.57 | .96 |
| Grade | n/a | n/a | .30 | n/a | n/a | .26 |
| 2 | 0.52 | 0.049-5.43 | .58 | 0.27 | 0.58-1.28 | .10 |
| 3 | 1.84 | 0.21-16.46 | .59 | 3.66 | 0.78-17.24 | .10 |
Abbreviations: CI = confidence interval; HR = hazard ratio; LN = lymph node; OS = overall survival; PFS = progression-free survival; SCC = squamous cell carcinoma.
∗
Regional LN involvement was associated with poorer PFS (P = .007).