Table 2.
Observed antibiotic resistance and genome-based antimicrobial resistance (AMR) prediction
|
Phenotypic resistance |
AMR prediction* |
Match |
Sensitivity† |
Specificity† |
|||||
|---|---|---|---|---|---|---|---|---|---|
|
S |
I |
R |
S |
I |
R |
||||
|
Ciprofloxacin (CIP) |
57 % |
0 % |
43 % |
58 % |
0 % |
42 % |
99 % |
99 % |
100 % |
|
Ceftriaxone (CRO) |
100 % |
0 % |
0 % |
62 % |
38 % |
0 % |
100 % |
na |
100 % |
|
Cefixime (CFM) |
99 % |
0 % |
1 % |
62 % |
32 % |
6 % |
95 % |
83 % |
95 % |
|
Azithromycin (AZM) |
58 % |
32 % |
10 % |
66 % |
31 % |
3 % |
66% |
58 % |
100 % |
|
Penicillin G (PCN) |
5 % |
65 % |
30 % |
37 % |
42 % |
22 % |
54 % |
74 % |
96 % |
|
Spectinomycin (SPX) |
100 % |
0 % |
0 % |
100 % |
0 % |
0 % |
100 % |
na |
100 % |
|
Tetracycline (TET) |
48 % |
19 % |
33 % |
12 % |
67 % |
22 % |
52 % |
74 % |
100 % |
*AMR prediction by Pathogenwatch.
†Intermediate susceptible observations and predictions were treated as susceptible in order to calculate sensitivity and specificity.
SIR, S, susceptible; I, intermediate susceptibility; R, resistant.