Table 1.
Selected structures of complexes of coronavirus spike glycoproteins or their fragments with the ACE2 receptor that were analyzed in this work. Abbreviation civ refers to the virus from civet, h to human, and hc to hybrid human‐civet proteins.
| PDB ID | Resol (Å) | R free | Space gr. | a (Å) | b (Å) | c (Å) | β (°) | Spike | Enzyme | Action |
|---|---|---|---|---|---|---|---|---|---|---|
| 6LZG | 2.5 | 0.214 | P41212 | 104.4 | 104.4 | 229.8 | CoV‐2 | hACE2 | – | |
| 6M0J | 2.45 | 0.227 | P41212 | 104.7 | 104.7 | 228.7 | CoV‐2 | hACE2 | – | |
| 6VW1 | 2.68 | 0.229 | P21 | 80.4 | 118.0 | 112.1 | 93.1 | CoV‐2 | hACE2 | Achesym, minor |
| 3SCI | 2.9 | 0.283 | P21 | 81.4 | 118.3 | 111.9 | 93.1 | SARS | hACE2 | Achesym, minor |
| 3SCK | 3.0 | 0.285 | P21 | 81.2 | 119.3 | 113.2 | 92.2 | SARS/civ | hcACE2 | Achesym, minor |
| 3SCL | 3.0 | 0.292 | P21 | 81.7 | 119.5 | 113.5 | 92.5 | SARS | hcACE2 | Achesym, minor |
| 2AJF | 2.9 | 0.275 | P21 | 82.3 | 119.4 | 113.2 | 92.0 | SARS | hACE2 | Achesym |
| 3D0H | 3.1 | 0.302 | P21 | 80.4 | 119.8 | 109.4 | 95.9 | SARS/civ | hcACE2 | Achesym, some |
| 3D0I | 2.9 | 0.278 | P21 | 80.4 | 119.8 | 109.7 | 95.5 | SARS/civ | hcACE2 | Achesym, some |
| 3D0G | 2.8 | 0.279 | P21 | 80.0 | 119.8 | 108.8 | 96.2 | SARS | hcACE2 | Achesym, some |
| 6M17 | 2.9/3.5 | cryo‐EM | CoV‐2 | hACE2 | – |