Table 4.
Pregnancy outcomes of women with COVID‐19 reported in case series and case reports included in systematic review
| Pregnancy complication | Mode of delivery | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Study | N | GDM | HPD | PE | HT | PP/PA | Not delivered at time of reporting | Miscarriage/termination | Delivered at time of reporting | CS | COVID‐19 as main CS indication | Vaginal | GA at delivery (weeks) | |
| Case series | ||||||||||||||
| Breslin (2020) 19 | 43 | NR | NR | NR | 0 | NR | 25 | 0 | 18 | 8 | 0/8 | 10 | NR | |
| Ferrazzi (2020) 26 | 42 | 6 | NR | NR | NR | NR | 0 | 0 | 42 | 18 | 10/18 | 24 | NR | |
| Hantoushzadeh (2020) 20 | 9‡ | NR | NR | NR | NR | NR | 2 | 0 | 7 | 6§ | 2/6 | 1¶ | 24–38 | |
| Liu (2020) 21 | 41 | 4 | 3 | 0 | 0 | NR | 25 | 0 | 16 | 16 | NR | 0 | NR | |
| Liu (2020) 22 | 13 | NR | NR | NR | 0 | NR | 3 | 0 | 10 | 10 | 5/10 | 0 | NR | |
| Liu (2020) 23 | 15 | 1 | 0 | 0 | 0 | 1 | 4 | 0 | 11 | 10 | NR | 1 | NR | |
| Liu (2020) 24 | 19 | NR | NR | NR | NR | NR | 0 | 0 | 19 | 18 | NR | 1 | 35 + 2 to 41 + 2 | |
| Wu (2020) 25 | 23 | 0 | 4 | 0 | 2 | 0 | 0 | 3 | 20 | 18 | NR | 2 | 31 + 5 to 40 | |
| Yan (2020) 11 | 99 | 7 | 4 | 3 | 0 | NR | 15 | 1 | 83 | 73 | 45/73 | 10 | 28 + 1 to 41 + 2 | |
| Total* | 295 | 18/220 (8.2) | 11/178 (6.2) | 3/178 (1.7) | 2/234 (0.9) | 1/38 (2.6) | 72/295 (24.4) | 4/295 (1.4) | 219/295 (74.2) | 171/219 (78.1) | 60/109 (55.0) | 48/219 (21.9) | 28–41 | |
| Case reports | ||||||||||||||
| Alonso Díaz (2020) 27 | 1 | 0 | 1 | 1 | NR | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 38 + 4 | |
| Alzamora (2020) 28 | 1 | NR | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 33 + 3 | |
| Buonsenso (2020) 29 , † | 2 | NR | NR | NR | NR | NR | 2 | 0 | 2 | 2 | 0 | 0 | 35 + 7, 38 + 3 | |
| Gidlöf (2020) 30 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 36 + 2 | |
| González Romero (2020) 31 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 29 | |
| Iqbal (2020) 32 | 1 | 0 | 0 | 0 | NR | 0 | 0 | 0 | 1 | 0 | — | 1 | 39 | |
| Juusela (2020) 33 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 0 | 34 + 1, 39 + 2 | |
| Kalafat (2020) 34 | 1 | NR | 0 | 0 | NR | NR | 0 | 0 | 1 | 1 | 1 | 0 | 35 + 5 | |
| Karami (2020) 35 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | — | 1 | 30 + 3 | |
| Kelly (2020) 36 | 1 | 0 | 0 | 0 | 0 | NR | 0 | 0 | 1 | 1 | 0 | 0 | 33 | |
| Lee (2020) 37 | 1 | NR | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 37 + 6 | |
| Lowe (2020) 38 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | — | 1 | 40 + 3 | |
| Schnettler (2020) 39 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 32 + 0 | |
| Vlachodimitropoulou Koumoutsea (2020) 40 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 36, 35 + 5 | |
| Zamaniyan (2020) 41 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 32 + 4 | |
Only first author is given for each study.
Data are presented as n, n/N, range or n/N (%) unless indicated otherwise.
Hantoushzadeh (2020) 20 excluded from calculation because not consecutive case series.
Additional information for this study retrieved from Buonsenso (2020) 53 .
Including two women with intrauterine fetal death (IUFD), who remained undelivered at time of maternal death (one with twin pregnancy).
Including one IUFD.
IUFD.
CS, Cesarean section; GA, gestational age; GDM, gestational diabetes mellitus; HPD, hypertensive disorder of pregnancy; HT, hypothyroidism; NR, not reported; PE, pre‐eclampsia; PP/PA, placenta previa/accreta.