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. 2020 Jul 2;21(21):2999–3025. doi: 10.1002/cbic.202000238

Figure 3.

Figure 3

Binding poses experimentally described for the DC‐SIGN CRD and four typical mannosylated and fucosylated oligosaccharides. Structures A, B and D have been solved by X‐ray crystallography. Model C is a representative structure obtained by MD and supported by NMR data. Sugars are colored as follows: Man: green, Fuc: magenta, Gal: yellow, Glc: blue. Residues F313, V351 and K368 are shown as sticks in all cases. A) Man4 (PDB ID: 1SL4). B) GlcNAc2Man3 (PDB ID: 1K9I). C) Blood group A type VI. [83] D) Lacto‐N‐fucopentaose III (PDB ID: 1SL5).