Table 4.
Comparison of patients clinical outcome and treated infections, according to Cmax/MIC ratio observed < or ≥ 8 on D1
| Overall population | Cmax/MIC on D1 | p | ||
|---|---|---|---|---|
| < 8 | ≥ 8 | |||
| Patientsa | (n = 93) | (n = 10) | (n = 83) | |
| Length of stay in intensive care unit (d) | 16 [2–123] | 16 [2–123] | 16 [2–96] | 0.80 |
| Mortality D28 | 23 (24.7) | 2 (20) | 21 (25.3) | 1 |
| Infectious episodes | (n = 98) | (n = 11) | (n = 87) | |
| Mortality D8 | 11 (11.2) | 2 (18.2) | 9 (10.3) | 0.60 |
| SOFA D8 | 3 [0–12] | 2 [0–6] | 3 [0–12] | 0.75 |
Data expressed in n (%) or median [min–max]
aComparison according to the Cmax/MIC ratio observed during the first episode of infection treated with amikacin