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The hypothetical molecular mechanism of WJ-39 in diabetic nephropathy. AR: aldose reductase; Nrf2: nuclear factor erythroid 2-related factor 2; NF-κB: nuclear factor-kappa B; NLRP3: nucleotide-binding and oligomerization domain-like receptor family pyrin domain-containing 3; TGF-β1: transforming growth factor-β1; ECM: extracellular matrix.
