Table 3.
Detailed information of major hub genes in PPI network.
| Gene names | Degree | Protein names |
|---|---|---|
| AKT1 | 73 | RAC-alpha serine/threonine-protein kinase |
| TP53 | 65 | Cellular tumor antigen p53 |
| MAPK1 | 63 | Mitogen-activated protein kinase |
| MAPK8 | 57 | Mitogen-activated protein kinase 8 |
| JUN | 57 | JUN protein |
| EGFR | 55 | Epidermal growth factor receptor (epidermal growth factor receptor tyrosine kinase domain) |
| VEGFA | 54 | Vascular endothelial growth factor A |
| IL-6 | 53 | Interleukin-6 |
| INS | 51 | Insulin |
| TNF | 49 | Tumor necrosis factor |
| MYC | 49 | V-myc myelocytomatosis viral oncogene homolog |