Table 5.
Parameters | Dose (mg kg−1) | |||
---|---|---|---|---|
0 | 500 | 1000 | 2000 | |
Male | ||||
Heart | 0.37 ± 0.17 | 0.37 ± 0.07 | 0.39 ± 0.12 | 0.40 ± 0.24 |
Kidney (R) | 0.37 ± 0.28 | 0.38 ± 0.33 | 0.35 ± 0.11 | 0.38 ± 0.24 |
Kidney (L) | 0.38 ± 0.26 | 0.38 ± 0.22 | 0.43 ± 0.12 | 0.40 ± 0.36 |
Liver | 3.5 ± 0.57 | 3.88 ± 0.22 | 4.03 ± 0.34 | 4.08 ± 0.69 |
Spleen | 0.30 ± 0.40 | 0.25 ± 0.13 | 0.25 ± 0.15 | 0.23 ± 0.49 |
Lung | 0.58 ± 0.36 | 0.51 ± 0.13 | 0.69 ± 0.40 * | 0.76 ± 0.57 * |
Female | ||||
Heart | 0.43 ± 0.10 | 0.38 ± 0.04 | 0.40 ± 0.13 | 0.37 ± 0.09 |
Kidney (R) | 0.35 ± 0.06 | 0.31 ± 0.18 | 0.35 ± 0.07 | 0.35 ± 0.06 |
Kidney (L) | 0.36 ± 0.06 | 0.39 ± 0.17 | 0.35 ± 0.05 | 0.36 ± 0.11 |
Liver | 4.63 ± 0.98 | 4.61 ± 0.62 | 4.43 ± 0.27 | 4.35 ± 0.56 |
Spleen | 0.27 ± 0.08 | 0.29 ± 0.17 | 0.27 ± 0.15 | 0.29 ± 0.14 |
Lung | 0.57 ± 0.16 | 0.77 ± 0.38 * | 0.74 ± 0.33 * | 0.76 ± 0.32 * |
* Significantly different from vehicle control at p < 0.05.