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Experimental design for the effect of VU-29 administered in three different combinations on long-time maintenance of ethanol-induced CPP (A). Data are shown as post-conditioning minus pre-conditioning time (s) spent in the drug-associated compartment in the CPP Test 2 (B). Dots represent individual measurements, the central horizontal mark is the mean, and error bars represent SEM. *** p < 0.001 vs. vehicle; ^^^ p < 0.001 vs. ethanol-treated group.
