Table 2.
Antidiarrheal activity of C. oxycantha extracts on castor oil-induced diarrhea.
Group | Dose (mg/kg (B.w)) | Mean ± SE | % of Inhibition | |
---|---|---|---|---|
Latency | Defecation | |||
Normal Control | 10 mL/kg | 0.50 ± 0.45 | 9.33 ± 1.45 | - |
Carthamus oxycantha | 200 | 1.75 ± 0.20 | 7.33 ± 1.76 * | 21.43 |
Carthamus oxycantha | 400 | 2.10 ± 0.50 | 5.20 ± 1.15 ** | 44.26 |
Standard (Loperamide) | 50 | 3.47 ± 1.20 | 3.66 ± 0.66 *** | 60.77 |
Data are represented as mean ± SEM, N = 05, * p < 0.05, ** p < 0.01, and *** p < 0.001. Significant when compared with control. The statistical test employed was a one-way ANOVA test followed by a Turkey’s multiple comparisons.