Table 1.
Enzyme Group | Genetic Location | Predominant Isolation Countries * | Isolation Source | Other Reported Species | Total Reported |
---|---|---|---|---|---|
OXA-23-like | Plasmid, chromosome | USA (564), India (125), South Korea (122) | Clinical (2,830) Environmental/other (1128) | Providencia alcalifaciens, Proteus mirabilis, Klebsiella pneumoniae, Citrobacter freundii, E. coli/Shigella, Serratia marcescens, Acinetobacter non-baumannii, Pseudomonas aeruginosa | 4048 |
OXA-24/40-like | USA (100), Spain (5) | Clinical (124) Environmental/other (21) | Acinetobacter non-baumannii, Klebsiella pneumoniae, Providencia rettgeri, Staphylococcus aureus | 162 | |
OXA-51-like | Germany (8), Brazil (8), Japan (6) | Clinical (39) Environmental/other (20) | Acinetobacter non-baumannii, Klebsiella pneumoniae | 88 | |
OXA-58-like | Plasmid, Chromosome |
USA (84), Spain (12), Thailand (8) | Clinical (90) Environmental/other (177) | Providencia alcalifaciens, Klebsiella pneumoniae, E. coli/Shigella, Proteus mirabilis, Enterobacter sp., Acinetobacter non-baumannii. | 284 |
OXA-143-like | Brazil (3) | Clinical (3) | Acinetobacter non-baumannii | 15 |
* The number of isolates was calculated using the US National Library of Medicine Pathogen Detection tool (https://www.ncbi.nlm.nih.gov/pathogens) and complemented using Blast [174]. Enzymes in each group have 90% identity and 96% coverage.