Table 2.
Genotype distributions of GAS5 gene polymorphisms in 860 controls and 430 patients with UCC.
| Variable | Controls (n = 860) n (%) | Patients (n = 430) n (%) | OR (95% CI) | AOR (95% CI) |
|---|---|---|---|---|
| rs145204276 | ||||
| Ins/Ins | 355 (41.3%) | 191 (44.4%) | 1.000 | 1.000 |
| Ins/Del | 388 (45.1%) | 191 (44.4%) | 0.915 (0.715–1.171) | 0.948 (0.678–1.324) |
| Del/Del | 117 (13.6%) | 48 (11.2%) | 0.763 (0.522–1.114) | 0.737 (0.435–1.247) |
| Ins/Del + Del/Del | 505 (58.7%) | 239 (55.6%) | 0.880 (0.696–1.111) | 0.900 (0.654–1.238) |
| rs55829688 | ||||
| TT | 412 (47.9%) | 208 (48.4%) | 1.000 (reference) | 1.000 (reference) |
| TC | 354 (41.2%) | 187 (43.5%) | 1.046 (0.820–1.335) | 0.948 (0.682–1.319) |
| CC | 94 (10.9%) | 35 (8.1%) | 0.738 (0.483–1.125) | 0.567 (0.304–1.055) |
| TC + CC | 448 (52.1%) | 222 (51.6%) | 0.982 (0.779–1.237) | 0.867 (0.633–1.188) |
The odds ratios (ORs) with their 95% confidence intervals were estimated by logistic regression models. The adjusted odds ratio (AOR) with their 95% confidence intervals were estimated by multiple logistic regression models after controlling for age, gender, and tobacco consumption.