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. 2020 May 20;40(5):683–692. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2020.05.11

3.

BUB1和相关基因的GO功能注释和KEGG通路富集

GO functional annotation and KEGG pathway enrichment of BUB1 and related genes

Categories Terms Function n P
Biological process GO:0007059 Chromosome segregation 18 < 0.01
GO:0051301 Cell division 20 < 0.01
GO:0098813 Cell cycle 17 < 0.01
GO:0000819 Nuclear fission 14 < 0.01
GO:0007049 Regulation of mitotic cellcycle 21 < 0.01
GO:1903047 Chromosome organization regulation 18 < 0.01
GO:0022402 Cellular circulation regulation 19 < 0.01
GO:0000280 Organelle regulation 15 < 0.01
GO:0051983 Immune system action 12 < 0.01
GO:0000070 Cells secrete 12 < 0.01
GO:0051276 Negative regulation of cellular protein metabolism 17 < 0.01
GO:0051783 Defense reaction 11 < 0.01
Cell components GO:0000775 The centromere region of the chromosome 17 < 0.01
GO:0000776 Spindle 16 < 0.01
GO:0000779 Microtubule cytoskeleton 15 < 0.01
GO:0000777 Cytosol 14 < 0.01
GO:0005819 The nucleus 12 < 0.01
GO:0043232 Membrane systems 21 < 0.01
GO:0015630 The cytoplasm 15 < 0.01
GO:0044430 The endoplasmic reticulum 15 < 0.01
GO:0005829 Nuclear lumen 20 < 0.01
GO:0032991 Kinetochore 19 < 0.01
GO:0005634 Extracellular space 20 < 0.01
GO:0044446 Secretory granules 21 < 0.01
GO:0031981 Nuclear plasma 15 < 0.01
Molecular function GO:0004674 Protein serine/threonine kinase activity 7 < 0.01
GO:0005524 In combination with ATP 8 < 0.01
GO:0140096 Protein catalytic activity 8 < 0.01
GO:0044877 Protein complex binding 5 < 0.01
KEGGpathways hsa04110 Cell cycle signaling pathways 10 < 0.01
hsa04114 Meiosis signaling pathway in oocytes 7 < 0.01
hsa04914 Oocyte maturation signaling pathway 5 < 0.01
hsa04115 P53-related signaling pathways 5 < 0.01