Table 1.
Patient characteristics (chi square tests; sex, two-parent family, parental education, tiredness, family history, presence anti-TPO. Independent t-test; age. Mann–Whitney test; Total Cholesterol (TC), high-density lipoprotein (HDL), cholesterol/HDL ratio, triglycerides (TG), low-density lipoprotein (LDL), height, weight and BMI).
| Intervention Group | Control Group | p-Value | |
|---|---|---|---|
| n = 29 | n = 32 | ||
| Male:female | 15:14 | 16:16 | 0.89 |
| Age in years (SD) | 7.7 (3.1) | 8.1 (3.3) | 0.67 |
| 2-Parents family | 27 (51%) | 26 (49%) | 0.23 |
| Parental education (only primary or high school) | 6 (20.6%) | 1 (3.3%) | 0.32 |
| Tiredness (according to parents) | 23 (79%) | 22 (73%) | 0.59 |
| Positive family history for thyroid diseases (%) | 16 (55%) | 15 (52%) | 0.55 |
| TSH start (mIU/L) (SD) | 6.14 (1.4) | 5.69 (1.4) | 0.15 |
| FT4 start (pmol/L) (SD) | 16.6 (2.1) | 15.7 (1.6) | 0.06 |
| Anti-TPO positive (%) start | 2 (7%) | 4 (12%) | 0.46 |
| Total Cholesterol (mmol/L) (median, IQR) | 4.2 (3.7–4.6) | 4.3 (3.8–4.9) | 0.28 |
| HDL-C (mmol/L) (median, IQR) | 1.4 (1.2–1.8) | 1.4 (1.2–1.8) | 0.80 |
| Cholesterol/HDL ratio (mmol/L) (median, IQR) | 3.0 (2.3–3.5) | 3.1 (2.4–4.0) | 0.61 |
| TG (mmol/L) (median, IQR) | 0.9 (0.7–1.3) | 1.0 (0.6–1.4) | 0.88 |
| LDL-C (mmol/L) (median, IQR) | 2.2 (1.8–2.4) | 2.4 (1.7–3.0) | 0.37 |
| Height (cm) (median, IQR) | 127 (113–139) | 132 (115–148) | 0.25 |
| Weigth (kg) (median, IQR) | 24.9 (21–34) | 31.1 (20–46) | 0.16 |
| BMI (kg/m2) (median, IQR) | 16.0 (15–17) | 17.0 (16–20) | 0.05 |