Table 3.

Correlations between the mRNA expression of all studied desaturase genes in all three tumor zones, using B2M gene as reference.

Studied Gene/ Location		FADS1			FADS2			FADS3			SCD			SCD5
		GTA	NC	PA	GTA	NC	PA	GTA	NC	PA	GTA	NC	PA	GTA	NC	PA
FADS1	GTA	1.00
	NC	0.26	1.00
	PA	0.48 *	0.15	1.00
FADS2	GTA	0.77 *	0.09	0.51	1.00
	NC	0.15	0.58 *	0.33	0.48	1.00
	PA	0.22	0.10	0.48 *	0.50 *	0.53 *	1.00
FADS3	GTA	0.10	−0.11	0.21	0.18	0.08	0.40	1.00
	NC	0.00	0.52 *	−0.01	0.14	0.21	0.37	0.40	1.00
	PA	−0.10	−0.03	0.43 *	0.12	0.23	0.37	0.71 *	0.29	1.00
SCD	GTA	0.58 *	0.16	0.13	0.68*	0.50	0.40	0.22	0.17	0.25	1.00
	NC	0.35	0.63 *	0.04	0.38	0.45 *	0.07	0.12	0.59 *	0.09	0.30	1.00
	PA	0.20	0.35	0.46 *	0.46	0.68 *	0.74 *	0.35	0.49 *	0.39	0.64 *	0.40	1.00
SCD5	GTA	0.65 *	−0.07	0.48 *	0.82 *	0.35	0.52 *	0.03	−0.05	−0.05	0.56 *	0.20	0.57 *	1.00
	NC	0.30	0.66 *	0.37	0.51 *	0.80 *	0.65 *	0.05	0.42	0.25	0.52 *	0.63 *	0.76 *	0.48	1.00
	PA	0.47 *	0.21	0.55*	0.68 *	0.62 *	0.70 *	0.16	0.08	−0.02	0.24	0.22	0.59 *	0.65 *	0.71 *	1.00

The values of Spearman’s rank correlation coefficients are given. * statistically significant correlation of the expression of two genes/locations (p < 0.05). GTA—growing tumor area; NC—necrotic core; PA—peritumoral area.