Table 4.

Flavonoid and (iso)flavonoid derivatives categorized as class B according to experimental MIC (10−20 μg·mL⁻). Class predicted by SAR is created from structural fragments, whereas QSAR predicted MIC uses experimental MIC in the algorithm.

Compounds	Class	Class Predicted SAR	pMIC	pMIC Predicted	Experimental MIC	QSAR Predicted MIC	Class Predicted QSAR
Neobavaisoflavone	B	A1	−1.3	−1.61	20.0	40.7	C
Dihydroauriculatin	B	A4	−1.15	−0.99	14.1	9.8	A
Eryvarin C	B	A4	−1.27	−1.44	18.6	27.5	C
Erystagallin A	B	B1	−1.04	−1.27	11.0	18.6	B
Eryzerin E	B	B1	−1.19	−1.27	15.5	18.6	B
Orientanol C	B	B1	−1.19	−1.65	15.5	44.7	C
Eryvarin V	B	B1	−1.27	−1.22	18.6	16.6	B
5−Hydroxysophoranone	B	B2	−1.1	−0.93	12.6	8.5	A
Abyssinone IV	B	B2	−1.1	−1.25	12.6	17.8	B
Erybraedin C	B	B3	−1.1	−1.03	12.6	10.7	A
Eryvarin D	B	B3	−1.1	−0.98	12.6	9.5	A
Ptorepterocarpan	B	B3	−1.1	−0.99	12.6	9.8	A
Eryzerin A	B	B3	−1.27	−1.25	18.6	17.8	B
Phaseollidin	B	B3	−1.39	−1.12	24.5	13.2	B
Eryvarin Y	B	B4	−1.27	−1.23	18.6	17.0	B
Citflavanone	B	B5	−1.1	−1.74	12.6	55.0	C
Glabrocoumarone A	B	B5	−1.1	−1.2	12.6	15.8	B
Erybraedin B	B	C4	−1.1	−1.04	12.6	11.0	B
Lupinifolin	B	D4	−1.1	−1.72	12.6	52.5	C