Figure 3.

Ticagrelor but not cangrelor induced an anti-apoptotic effect. Cells were treated with ticagrelor 1 µM, 10 µM or with cangrelor 1 µM, 10 µM and 50 µM. Results are expressed as means ± sem (n = 6/group) of relative cleaved caspase 3 expression (%) in the human umbilical vein endothelial cells (HUVECs) after 2 h of hypoxia. **: p < 0.01 compared to control without any treatment.