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. 2020 May 20;10(5):790. doi: 10.3390/biom10050790

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Dose-response curves of Figainin 2: The X-axis indicates the log of Figainin 2 concentration (molar); the right Y-axis shows the normalized antiviral activity in percentage (in black), which represents the inhibition of infection in relation to positive control; and the right Y-axis shows the cell ratio or cell survival (in red). (A) chikungunya virus (CHIKV) 181/25, EC₅₀ = 17.9 μM, CC₅₀ = 49.0 μM, and SI = 2.88; (B) Dengue serotype 4 virus, EC₅₀ = 20.8 μM, CC₅₀ = 50.1 μM, and SI = 2.41; and (C) Yellow Fever Virus, EC₅₀ = 21.8 μM, CC₅₀ = 26.4 μM, and SI = 1.21.