Table 4.
Antimicrobial and anti-T cruzi activities of Figainin 2.
| Microorganisms | Figainin 2 (µM) |
|---|---|
| Gram-negative bacteria (MIC) | |
| E. coli (ATCC 25922) | 8 |
| P. aeruginosa (ATCC 27853) | 32 |
| K. pneumoniae (ATCC 13883) | 8 |
| K. pneumoniae carbapanemase (KPC) MR | 16 |
| Gram-positive bacteria (MIC) | |
| S. aureus (ATCC 25923) | 8 |
| E. faecalis (ATCC 29212) | 8 |
| S. epidermidis (ATCC 12228) | 4 |
| E. casseliflavus (ATCC 700327) | 4 |
| Yeast (MIC) | |
| C. albicans (ATCC 90028) | NA |
| C. parapsilosis (ATCC 22019) | NA |
|
Trypanosoma epimastigotes (IC50)
T. cruzi |
6.32 |
MIC: minimal inhibitory concentration; MR: multi-resistant strain; NA: no activity at 128 µM and IC50: half maximal inhibitory concentration.