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The effect of cHP4 on apoptotic and necrotic cell death in a cellular AD model (Hoechst 33258): (A) control (−) group, (B) Aβ1-42 (20 µM) + Aβ1-42, (C) cHP4 (50 µM) + Aβ1-42, and (D) cHP4 (100 µM) + Aβ1-42. Arrows show necrotic cells with damaged chromosomal structure.
