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Status of the different parameters evaluated in the urine of the rats of the different groups.
| Insulin-Loaded NPs (n = 5) |
Empty NPs (n = 5) |
Non-Encapsulated insulin, p.o. (n = 3) |
PBS (n = 2) |
|
|---|---|---|---|---|
| Leucocytes | - | - | - | - |
| Urobilinogen | N | N | N | N |
| Bilirubin | - | - | - | - |
| Hematuria | +/- | +/- | - | +/- |
| Nitrite | - | - | - | - |
| pH | 5.4 | 5.9 | 5.3 | 5.5 |
| Density | 1.03 | 1.02 | 1.03 | 1.03 |
| Proteinuria | +/- | +/- | +/- | +/- |
| Glycosuria | - | - | - | - |
| Ketonic bodies | - | - | +/- | +/- |
+, one positive case; −, negative result; N, no change.
