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. 2020 May 13;17(10):3395. doi: 10.3390/ijerph17103395

Table 2.

Top three frequent unique combination clusters for patients with multimorbidity, stratified by total number of chronic diseases and by sex.

Age Group Rank Dyads of Morbidities Triads of Morbidities
Male Female Male Female
Combination n (%) Combination n (%) Combination n (%) Combination n (%)
All ages; male: n = 955,257, female: n = 1,141,893
1 OARA + HT 282,995 (29.6) OARA + HT 429,553 (37.6) IHD + OARA + HT 194,735 (20.4) IHD + OARA + HT 276,928 (24.3)
2 IHD + HT 272,230 (28.5) IHD + OARA 383,889 (33.6) COPD + OARA + HT 132,923 (13.9) COPD + OARA + HT 204,352 (17.9)
3 IHD + OARA 255,872 (26.8) IHD + HT 324,411 (28.4) IHD + COPD + OARA 130,557 (13.7) IHD + COPD + OARA 198,311 (17.4)
45–59 years; male: n = 446,540, female: n = 602,035
1 OARA + HT 71,626 (16.0) OARA + HT 164,234 (27.3) IHD + OARA + HT 35,719 (8.0) IHD + OARA + HT 79,290 (13.2)
2 DM + HT 65,518 (14.7) COPD + OARA 120,912 (20.1) DM + OARA + HT 24,719 (5.5) COPD + OARA + HT 70,249 (11.7)
3 IHD + HT 63,979 (14.3) IHD + OARA 118,355 (19.7) COPD + OARA + HT 24,367 (5.5) IHD + COPD + OARA 58,021 (9.6)
≥60 years; male: n = 602,035, female: n = 539,858
1 OARA + HT 211,369 (35.1) IHD + OARA 265,534 (49.2) IHD + OARA + HT 159,016 (26.4) IHD + OARA + HT 197,638 (36.6)
2 IHD + HT 208,251 (34.6) OARA + HT 265,319 (49.1) IHD + COPD + OARA 110,904 (18.4) IHD + COPD + OARA 140,290 (26.0)
3 IHD + OARA 206,397 (34.3) IHD + HT 230,795 (42.8) COPD + OARA + HT 108,556 (18.0) COPD + OARA + HT 134,103 (24.8)

Abbreviations: IHD, ischaemic heart disease; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; OARA, osteoarthritis and rheumatoid arthritis; HT, hypertension.