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. 2020 May 25;10(5):809. doi: 10.3390/biom10050809

Table 2.

Summary of granted patents on trehalose for dry eye.

Patent General Field of Protection 1 Designated
Country
JP4033510 (B2) Trehalose for protecting cornea and used as eye drops JP
EP1192947 (B1) Trehalose in treatment and/or prevention of symptom or sign of Sjögren syndrome DE FR GB
EP1649860 (B1) Trehalose in treatment of dry eye as a clinical symptom of Sjögren syndrome DE FR GB
US6555526 (B2) Ophthalmic pharmaceutical composition with trehalose for treatment and/or prevention of symptom and sign in dry eye in Sjögren syndrome US
US7732425 (B2) Method for treating dry eye (Sjögren syndrome) with trehalose in the form of eyewash solution US
CA2355814 (C) Ophthalmic pharmaceutical composition with trehalose for treatment and/or prevention of symptom or sign of Sjögren syndrome CA
AU781975 (2001065453) (B2) Ophthalmic pharmaceutical composition with trehalose for treatment or prevention of symptom or sign of Sjögren syndrome AU
KR100776124 (B1) Trehalose in treatment and/or prevention of symptom and sign in dry eye in Sjögren syndrome KR
TWI291350 (B) Trehalose in treatment or prevention of symptom and sign of Sjögren syndrome TW
JP4982643 (B2) Trehalose in treatment and/or prevention of symptom or sign of Sjögren syndrome JP
EP3110425 (B1) Trehalose (as a diholoside) with 100–800 kDa HA for treating ophthalmic diseases such as dry eye Most EPO countries

1 Descriptive presentation of patent claim(s).