State-of-the-art-parameters obtained from HRCT found in recent literature. In the specific, high-attenuation area (HAA)% [9] is defined as areas with attenuation values greater than −200 Hounsfield Unit (HU). HAA_A% [10] is defined as the percentage of the whole lung volume with a density between −250 and −600 HU. Pulmonary fibrosis fraction (PFF), normally attenuated lung (NL), HAA, LAA, and HAA parameters are expressed in percentage values (%) while kurtosis, skewness, mean lung density, median, and variance are expressed in absolute values.