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. Author manuscript; available in PMC: 2020 Jun 8.
Published in final edited form as: Basic Res Cardiol. 2019 May 31;114(4):28. doi: 10.1007/s00395-019-0737-y

Fig. 2.

Fig. 2

E2F1 deficiency in naïve mice does not affect O-GlcNAcylation or cardiac mass. Cardiac tissue from naïve, male E2f1+/+(n = 4) and E2f1−/−(n = 4) mice was harvested at 10–16 weeks of age. E2f1 mRNA expression in E2f1+/+ and E2f1−/− hearts (a; p < 0.00001). Expression of markers of HBP and metabolism (b). Gravimetric analysis of heart weight to body weight (c) and heart weight to tibia length (d). Cardiac expression of OGT (e), OGA (f), total protein O-GlcNAcylation (g). An unpaired Student’s t test was used to determine significance between E2f1+/+ and E2f1−/− groups