. 2020 Jun 8;21:505. doi: 10.1186/s13063-020-04445-5

Table 1.

REOX trial inclusion and exclusion criteria

Inclusion criteria	Exclusion criteria
• Patients over 18 years of age • Patients with leg ulcers (venous, ischaemic, traumatic or diabetic foot ulcer) • Patients with dehisced surgical wounds healing by second intention • Patients with pressure ulcers • Wound area between 1 and 250 cm² (wounds larger than 250 cm² are very unusual and outside the scope of this kind of treatment and therefore we decided to exclude it since such a large wound could be more difficult to heal)	• Systemic inflammatory disease or oncological disease • Wounds with clinical signs of infection • Terminal situation (life expectancy less than 6 months) • Ulcers from other aetiologies: tumours, infectious • Wounds treated with negative pressure therapy • Pregnancy • History of sensitivity or allergy to any of the components of the study dressing

Inclusion criteria

Exclusion criteria

• Patients over 18 years of age

• Patients with leg ulcers (venous, ischaemic, traumatic or diabetic foot ulcer)

• Patients with dehisced surgical wounds healing by second intention

• Patients with pressure ulcers

• Wound area between 1 and 250 cm² (wounds larger than 250 cm² are very unusual and outside the scope of this kind of treatment and therefore we decided to exclude it since such a large wound could be more difficult to heal)

• Systemic inflammatory disease or oncological disease

• Wounds with clinical signs of infection

• Terminal situation (life expectancy less than 6 months)

• Ulcers from other aetiologies: tumours, infectious

• Wounds treated with negative pressure therapy

• Pregnancy

• History of sensitivity or allergy to any of the components of the study dressing