Table 1.
HucMDEs relieve liver dysfunction and improve lipid profile in T2DM rats
Control + PBS | T2DM + PBS | T2DM + HDEs | T2DM + HucMDEs | |
---|---|---|---|---|
ALT (IU/l) | 66.26 ± 5.10 | 100.62 ± 6.13** | 103.71 ± 7.16 | 82.13 ± 6.13# |
AST (IU/l) | 195.23 ± 12.05 | 332.51 ± 16.58*** | 340.72 ± 18.45 | 293.05 ± 11.25# |
TC (mmol/l) | 1.95 ± 0.08 | 2.94 ± 0.14*** | 2.88 ± 0.15 | 2.16 ± 0.11## |
TG (mmol/l) | 0.78 ± 0.06 | 1.54 ± 0.08*** | 1.63 ± 0.10 | 1.23 ± 0.09# |
After STZ induction and HDEs, HucMDE treatment for another 2 months, rats were anesthetized with chloral hydrate. Blood was collected to measure the levels of liver function (ALT alanine aminotransferase, AST aspartate aminotransferase) and the levels of lipid (TC total cholesterol, TG triglyceride). Data were presented as mean ± SD (n = 7). *P < 0:05; **P < 0:01; ***P < 0.001 (compared with the control group), #P < 0:05; ##P < 0:01; ###P < 0.001 (compared with the T2DM + HDEs group)