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. 2020 Jun 8;17:37. doi: 10.1186/s12954-020-00377-0

Table 4.

Side-effect profile of medical cannabis use

Side-effect Severity
Mild and tolerable Severe and/or intolerable
Dry mouth (n = 977) 601 (61.5%) 23 (2.4%)
Increased appetite (n = 976) 578 (59.2%) 47 (4.8%)
Drowsy (n = 976) 534 (54.7%) 13 (1.3%)
Eye irritation (n = 974) 294 (30.2%) 8 (0.8%)
Lack of energy or fatigue (n = 973) 287 (29.5%) 20 (2.1%)
Anxiety (n = 974) 228 (23.4%) 23 (2.4%)
Memory impairment (n = 973) 227 (23.3%) 16 (1.6%)
Dehydration (n = 975) 220 (22.6%) 9 (0.9%)
Confusion (n = 975) 144 (14.8%) 9 (0.9%)
Respiratory complaints (n = 973) 141 (14.5%) 5 (0.5%)
Dizzy (n = 974) 137 (14.1%) 6 (0.6%)
Residual bad taste in mouth (n = 973) 135 (13.9%) 12 (1.2%)
Decreased Appetite (n = 975) 127 (13.0%) 8 (0.8%)
Paranoia (n = 973) 111 (11.4%) 9 (0.9%)
Racing heart or palpitations (n = 972) 106 (10.9%) 11 (1.1%)
Sweating (n = 974) 90 (9.2%) 10 (1.0%)
Depressed (n = 974) 87 (8.9%) 15 (1.5%)
Headaches (n = 973) 73 (7.5%) 11 (1.1%)
Sleep disturbance (n = 973) 72 (7.4%) 14 (1.4%)
Diarrhea (n = 974) 65 (6.7%) 7 (0.7%)
Constipation (n = 974) 52 (5.3%) 7 (0.7%)
Nasal Complaints (n = 973) 46 (4.7%) 8 (0.8%)
Gastro-intestinal irritation (n = 973) 44 (4.5%) 7 (0.7%)
Allergy (n = 974) 41 (4.2%) 5 (0.5%)
Panic Attacks (n = 973) 38 (3.9%) 8 (0.8%)
Shaking/tremor (n = 972) 37 (3.8%) 4 (0.4%)
Nausea/vomiting (n = 973) 36 (3.7%) 6 (0.6%)
Delusion (n = 974) 24 (2.5%) 4 (0.4%)
Hallucinations (n = 973) 22 (2.3%) 3 (0.3%)
Cannabis hyperemesis (n = 974) 12 (1.2%) 8 (0.8%)
Other (n = 970) 3 (0.3%) 11 (1.1%)