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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Expert Opin Drug Deliv. 2020 Feb 19;17(4):439–461. doi: 10.1080/17425247.2020.1729119

Table 2:

Functional assessment of pulmonary arterial hypertension

NYHA Class WHO Class Activity Limitations
1 I None
2 II Sight limitation of activity
3 III Marked limitation of activity
4 IV Symptoms with any activity or at rest; discomfort is increased by any physical activity

NYHA: New York Heart Association; WHO: World Health Organization.