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. 2020 May 21;10(5):898. doi: 10.3390/ani10050898

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of quercetin on recognition and spatial memory in AFB1 mice. Group I (control); Group II (veh + control); Group III (quercetin-only); Group IV (AFB1); Group V (afb1 + quercetin). Novel object recognition (NOR) and Morris water maze (MWM) tests were evaluated. (A) Exploration time in seconds; (B) escape latency; (C) frequency in the platform quadrant/min. Quercetin treatment was able to increase the exploration time for novel object recognition compared to the AFB1 group (A); to increase the time to finding the platform (B); as well as the frequency time around and within the target quadrant of the platform (C), compared to controls. Values are mean ± SEM of 8 mice/group. * p < 0.05 vs. veh + control group; # p < 0.05 vs. AFB1 + quercetin.