Table 2.
Complete blood count and serum chemistry values of cats belonging to the three study groups: Healthy (n = 22), FeMV (n = 14) and CKD (n = 21).
| Variable | RI | Healthy (n = 22) | FeMV (n = 14) | CKD (n = 21) | p Value |
|---|---|---|---|---|---|
| Hct % | 32–48 | 38.3 (33.3–48.7) | 32.0 (19.9–41.4) | 27.0 (17.7–40.1) | <0.001 * |
| WBCs cells/mm³ | 4800–14,900 | 8600 (4980–18,830) | 16,345 (7990–23,340) | 9660 (5480–27,970) | <0.001 ¶ |
| Neutrophils cells/mm³ | 1600–10,000 | 4710 (1570–13,520) | 9320 (4080–16,870) | 6270 (2740–24,790) | <0.001 * |
| Lymphocytes cells/mm³ | 900–5600 | 3050 (1150–4610) | 4530 (1660–9700) | 1760 (800– 7770) | <0.001 * |
| Monocytes cells/mm³ | 0–650 | 135.0 (50.0–490.0) | 470.0 (0.0–920.0) | 240.0 (70.0–870.0) | <0.001 * |
| Eosinophils cells/mm³ | 60–1470 | 645 (60–1260) | 955 (330–3910) | 490 (200–1060) | 0.009 ¶ |
| Platelets cells/mm³ | 150,000–500,000 | 208,000 (45,000–563,000) | 362,000 (58,000–615,000) | 332,000 (95,000–618,000) | 0.033 † |
| Basophils cells/mm³ | 0–60 | 20 (0–40) | 20 (10–60) | 10 (0–30) | <0.001 ‡ |
| Creatinine mg/dL | 0.8–1.6 | 1.46 (0.78–1.90) | 0.82 (0.67–2.13) | 2.98 (1.52–9.49) | <0.001 * |
| Creatinine > 1.6 mg/dL, n (%) | – | – | 1/14 (7%) | 19/21 (90%) | <0.001 |
| Urea mg/dL | 30–65 | 46.48 (31.47–73.01) | 45.35 (30.20–63.30) | 99.4 (41.51–318.82) | <0.001 ‡ |
| SDMA µg/dL | <18 | 12.5 (7.0–18.0) | 10.0 (6.0–15.0) | 21.5 (7.0–50.0) | <0.001 ‡ |
| SDMA ≥ 18 µg/dL, n (%) | – | – | 0/14 | 12/18 (67%) | <0.001 * |
| Total calcium mg/dL | 8.5–10.5 | 9.75 (8.80–10.80) | 9.20 (8.24–10.38) | 10.10 (8.30–11.60) | 0.004 ¶ |
| Ionized calcium mmol/L | 1.19–1.38 | 1.27 (1.07–1.34) | 1.25 (0.80–1.40) | 1.32 (1.07–1.50) | 0.001 ‡ |
| Phosphate mg/dL | 2.5–6.2 | 4.4 (3.0–6.1) | 5.43 (3.79–6.50) | 4.9 (4.0–12.3) | 0.010 † |
| Sodium mEq/L | 145–155 | 151.0 (147.0–155.0) | 149.0 (147.0–154.0) | 151.0 (143.0–157.0) | 0.299 |
| Chloride mEq/L | 110–123 | 119.0 (113.0–129.0) | 120.5 (117.0–125.0) | 116.6 (108.4–125.0) | 0.022 † |
| Potassium mEq/L | 3.4–5.1 | 4.2 (3.4–4.9) | 4.93 (4.08–5.38) | 4.2 (3.1–4.8) | <0.001 ¶ |
| Magnesium mg/dL | 1.9–2.8 | 2.30 (2.12–2.48) | 2.32 (2.04–2.72) | 2.27 (1.80–3.66) | 0.952 |
| Total proteins g/dL | 6.5–8.8 | 7.72 (7.06–8.89) | 7.87 (7.05–9.12) | 7.51 (5.36–9.97) | 0.790 |
| Albumin g/dL | 2.6–4.0 | 3.6 (2.0–4.0) | 3.1 (2.5–3.7) | 3.0 (2.3–3.4) | <0.001 † |
| A:G | 0.52–1.20 | 0.85 (0.58–1.28) | 0.63 (0.37–0.87) | 0.67 (0.37–0.90) | 0.001 † |
| Glucose mg/dL | 65–148 | 99.5 (71.0–240.0) | 85.0 (62.0–193.0) | 106.0 (72.0–148.0) | 0.055 |
| AST U/L | 9–40 | 25.5 (16.0–157.0) | 23.5 (5.0–65.0) | 28.0 (17.0–79.0) | 0.419 |
| ALT U/L | 20–72 | 47.5 (33.0–92.0) | 55.0 (20.0–117.0) | 58.0 (20.0–224.0) | 0.309 |
| GGT U/L | 0–4 | 0.1 (0.1–0.6) | 0.1 (0.0–1.3) | 0.1 (0.1–2.3) | 0.590 |
| ALP U/L | 20–140 | 69.0 (22.0–163.0) | 26.5 (13.0–120.0) | 45.0 (16.0–128.0) | <0.001 * |
| Total bilirubin mg/dL | 0–0.35 | 0.18 (0.10–0.31) | 0.08 (0.05–0.20) | 0.19 (0.14–0.32) | <0.001 ¶ |
| Total cholesterol mg/dL | 59–230 | 130.5 (45.0–370.0) | 86.0 (55.0–142.0) | 195.0 (81.0–478.0) | <0.001 * |
Data are reported as median and range (in brackets); FeMV = Feline morbillivirus; CKD = chronic kidney disease; RI = reference interval; Hct = haematocrit value; WBCs = white blood cells; SDMA = symmetric dimethylarginine; A:G = albumin:globulin ratio; AST = aspartate transaminase; ALT = alanine transaminase; GGT = gamma(γ)–glutamyltransferase; ALP = alkaline phosphatase; * Statistically significant difference among the three study groups; † Statistically significant difference in healthy compared with CKD and FeMV cats; ‡ Statistically significant difference in CKD compared with healthy and FeMV cats; ¶ Statistically significant difference in FeMV compared with CKD and healthy cats.