Table 6.

Antirhea borbonica prevents MGO-induced impairments in red blood cell deformability.

	RBC	RBC + Ab	RBC + MGO	RBC + MGO + Ab
Elongation parameters
EImax	0.428 ± 0.038	0.492 ± 0.026	0.113 ± 0.022 ***	0.239 ± 0.103 ##
SS1/2	4.447 ± 0.978	2.300 ± 0.090	12.259 ± 4.284 **	14.197 ± 2.765
Osmoscan parameters
EIos-max	0.494 ± 0.066	0.495 ± 0.057	0.206 ± 0.035 **	0.302 ± 0.032 #
Eios-min	0.200 ± 0.064	0.200 ± 0.040	0.226 ± 0.055	0.192 ± 0.002
rEI	2.669 ± 0.660	2.573 ± 0.719	0.970 ± 0.052 *	1.572 ± 0.237

Maximum elongation index (EI_max) and shear stress values applied at the half elongation (SS1/2) were calculated from deformability curve. Minimum elongation index (EI os-min) and maximum elongation index (EI os-max) values obtained from Osmoscan curves displayed on Figure 2A,B. The ratio of maximal and minimal EI values was calculated as follows—rEI = Ei_os-max/Ei_os-min. All data are expressed as mean ± SEM of at least three independent experiments. *Effect of MGO on red blood cells (vs. RBC), * p < 0.05, ** p < 0.01, *** p < 0.001. ^# Effect of Ab on glycated red blood cells (vs. RBC + MGO), ^# p < 0.05, ^## p < 0.01.