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. 2020 May 19;9(5):440. doi: 10.3390/antiox9050440

Table 3.

Plasma kinetic parameters for EGCG after the three preparations.

Parameters G Teavigo® Teavigo® with Breakfast FontUp®
AUC0–360
(μg/mL/kg/6 h)

3.9 ± 4.1
3.3 ± 1.1
1.5 ± 0.6
2.4 ± 1.1
0.6 ± 0.1 **
0.8 ± 0.2 **
Cmax (ng/mL/kg)
5.9 ± 4.1
6.7 ± 1.7
3.9 ± 1.3
4.5 ± 2.1
0.9 ± 0.1 **
1.3 ± 0.3 **
Cav (ng/mL/kg)
3.0 ± 2.6
3.7 ± 2.3
1.5 ± 1.5
2.1 ± 2.0
0.6 ± 0.2 **
0.9 ± 0.4 **
Cmin (ng/mL/kg)
1.5 ± 1.4
2.2 ± 1.1
0.7 ± 0.4
2.2 ± 1.6
0.3 ± 0.1 *
0.3 ± 0.0 *
T1/2 (min)
154.2 ± 27.9
117.2 ± 53.5
93.1 ± 36.2 *
111.4 ± 39.1
191.7 ± 66.4
132.9 ± 27.9
Tmax (min)
120 (90–180)
90 (60–120)
120 (90–180)
180 (120–360)
90 (60–90)
120 (90–120)

Values are means ± standard deviations for the 10 participants (n = 10), except for Tmax (median with the minimum and maximum time observed). * Value is significantly different from the other values in the row at the level of p < 0.05. ** Value is significantly different from the other values in the row at the level of p < 0.001. Abbreviations: G = gender; min = minutes; h = hours; ♂ = man; ♀ = women; AUC0–360 = area under the curve from 0 to 6 h; Cmax = maximum concentration; Cav = average concentration; Cmin = minimum concentration (at the end of the treatment); T1/2 = half-life; Tmax = time required to reach the maximal concentration.