Relative body weight gain during 5 months exposure of mice to HFSD and SPRD with and without APF addition. Data were subjected to two-way repeated-measures ANOVA (between-subjects factor: feed treatment (n = 8); four levels: HFSD, HFSD + APF, SPRD and SPRD + APF, degree of freedom was 3, F = 9.8 and p < 0.001; within-subject factor: time; five levels: 1, 2, 3, 4 and 5 months; degree of freedom was 4, F = 202.3 and p < 0.001; interaction “feed treatment × time”; degree of freedom was 12, F = 16.0 and p < 0.001); different uppercase letters within the same time indicate a significant difference of means, according to Tukey’s HSD test (p < 0.05).