Table 5.
Effect of 150 days of high-fat and sucrose diet with 10 mg of APF supplementation (HFSD+APF10) on glycaemic status food, body weight gain, water, food and energy intake, food efficiency ratio per food (FED1) and per energy intake (FED2), and glucose tolerance in OGTT (AUC) of C57BL/6J mice in comparison to HFSD without APF addition (HFSD) and to the standard pellet rodents diet with (SPRD+APF10) and without the addition of APF (SPRD).
| Parameter | HFSD + APF10 | HFSD | SPRD | SPRD + APF10 | F | p |
|---|---|---|---|---|---|---|
| Glycemia (mmol/L) | 7.6 ± 1.5 b | 12.4 ± 2.1 a | 8.9 ± 2.3 b | 8.9 ± 0.6 b | 8.3 | 0.001 |
| Body weight gain (g) | 4.5 ± 1.3 b | 11.5 ± 2.3 a | 11.1 ± 1.3 a | 6.7 ± 1.9 b | 22.5 | <0.001 |
| Water intake (mL/d) | 8.56 ± 0.36 | 8.44 ± 0.42 | 8.56 ± 0.36 | 8.39 ± 0.23 | 0.28 | 0.838 |
| Food intake (g/d) | 1.99 ± 0.03 b | 1.97 ± 0.05 b | 2.12 ± 0.03 a | 2.10 ± 0.04 a | 20.5 | <0.001 |
| Energy intake (kcal/d) | 15.2 ± 0.2 a | 15.0 ± 0.3 a | 6.4 ± 0.1 b | 6.3 ± 0.1 b | 3559.7 | <0.001 |
| FER1 ** (g/g) | 0.015 ± 0.004 b | 0.039 ± 0.008 a | 0.035 ± 0.004 a | 0.021 ± 0.006 b | 19.2 | <0.001 |
| FER2 *** (×10−3 g/kcal) | 2.0 ± 0.6 c | 5.1 ± 1.0 b | 11.6 ± 1.4 a | 7.1 ± 2.0 b | 53.3 | <0.001 |
| AUC (mM*h) | 19.2 ± 2.0 b | 29.0 ± 3.6 a | 16.3 ± 3.7 b | 19.9 ± 4.5 b | 14.3 | <0.001 |
* The values are represented as mean ± SD (glycaemia, body weight gain, FER1, FER2 and AUC: n = 8; liquid intake, food intake and energy intake: n = 21). Data were subjected to one-way ANOVA (between-subjects factor: feed treatment; four levels: HFSD, HFSD + APF10, SPRD and SPRD + APF10, degree of freedom was 3), different superscripts within the same row indicate a significant difference of means, according to Tukey’s HSD test (p < 0.05). ** FER1—feed efficiency ratio (weight gain/food intake). *** FER2—feed efficiency ratio (weight gain/energy intake).