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. 2020 May 21;9(5):446. doi: 10.3390/antiox9050446

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The expression of phase detoxifying enzymes. (A,B) The effect of myricetin (15 mg/kg) and B[a]P (2 mg/kg) treatment on CYP1A1 and CYP1B1 enzyme expression in the liver of Sprague-Dawley rats. (C) The effect of myricetin (10 μM) and B[a]P (10 μM) treatment on CYP1A1, GST, and ABCC2 enzyme expression in HepG2 cells. (D) Quantitative evaluation of relative protein expression of CYP1A1, GST, and ABCC2. All treatment groups are significantly different when compared with controls (** p < 0.01, *** p < 0.001) and B[a]P (### p < 0.001). Tukey’s multiple comparison test. M: myricetin.