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Simplified scheme of catalysis of cytochrome P450 (CYP) system; the CYPs receive two electrons derived from nicotinamide adenine dinucleotide phosphate (NADPH) through cytochrome P450 reductase (CPR) to catalyze the oxidation reaction R + O2 + NADPH → RO + H2O + NADP+; where R is the substrate and RO is the product of the oxidation reaction.
