Table 1. Demographic and perioperative data (N = 32).
All data are expressed as means ± SD.
| Parameters | Groups | Significance(P) | |||
|---|---|---|---|---|---|
| Placebo | Dex0.5 | Dex1 | Dex2 | ||
| Age(year) | 55.5 ± 11.9 | 55.6 ± 13.0 | 56.9 ± 8.9 | 56.3 ± 12.3 | 0.960 |
| ASA I/II(n) | 27/5 | 26/6 | 27/5 | 27/5 | 0.982 |
| Gender(male/female) | 15/17 | 17/15 | 17/15 | 15/17 | 0.919 |
| Weight(kg) | 62.8 ± 11.4 | 65.0 ± 11.5 | 60.1 ± 9.6 | 60.1 ± 10.4 | 0.204 |
| Height(cm) | 164.4 ± 7.6 | 167.3 ± 7.7 | 165.1 ± 5.6 | 164.4 ± 5.2 | 0.259 |
| Operative site(Right/Left) | 14/18 | 13/19 | 14/18 | 13/19 | 0.988 |
| Operational time(min) | 117.9 ± 25.8 | 116.3 ± 25.9 | 112.3 ± 21.8 | 111.8 ± 19.0 | 0.648 |
| Crystalloid(ml) | 571.9 ± 172.7 | 521.9 ± 131.3 | 562.5 ± 164.1 | 553.1 ± 158.6 | 0.611 |
| Colloid(ml) | 440.6 ± 126.6 | 462.5 ± 100.8 | 435.9 ± 133.3 | 425.6 ± 128.4 | 0.675 |
| Urine(ml) | 168.1 ± 38.1 | 184.1 ± 43.5 | 168.1 ± 53.5 | 163.4 ± 45.6 | 0.291 |
| PH | 7.41 ± 0.03 | 7.41 ± 0.02 | 7.40 ± 0.03 | 7.40 ± 0.02 | 0.978 |
| PaO2(mmHg) | 84.3 ± 5.8 | 83.6 ± 6.3 | 82.9 ± 4.8 | 82.3 ± 6.2 | 0.547 |
| PaCO2(mmHg) | 35.3 ± 1.5 | 35.3 ± 1.5 | 35.2 ± 1.4 | 35.0 ± 1.0 | 0.791 |
| Hb(mg l−1) | 117.2 ± 12.0 | 117.2 ± 11.7 | 118.3 ± 12.5 | 118.8 ± 11.9 | 0.934 |
| FEV1(%) | 80.5 ± 10.3 | 82.0 ± 9.5 | 79.2 ± 10.4 | 80.0 ± 8.5 | 0.705 |
| FVC(% ) | 88.2 ± 8.5 | 88.8 ± 7.8 | 86.1 ± 8.9 | 86.2 ± 6.9 | 0.417 |
| FEV1/FVC(%) | 84.3 ± 8.5 | 85.6 ± 8.2 | 83.7 ± 8.7 | 84.0 ± 7.5 | 0.809 |
Notes.
Compared with Placebo group.
*
P < 0.05.
- ASA
- American society of anesthesiologists physical status
- PH
- Hydrogen ion concentration
- PaO2
- Arterial oxygen partial pressure;
- PaCO2
- Arterial partial pressure of carbon dioxide
- Hb
- Hemoglobin concentrations
- FEV1
- Forced expiratory volume in one second
- FVC
- Forced vital capacity