Skip to main content
. 2020 May 15;21(10):3508. doi: 10.3390/ijms21103508

Figure 2.

Figure 2

(A–C): microRNAs in myostatin treated VSMCs relative to untreated control (100%). (A)—miR-433-3p expression in VSMCs treated with 10 nM and 20 nM myostatin only showed a downregulation at 10 nM treatment (p = 0.04). (B)—miR-494-3p expression in VSMCs treated with 10 and 20 nM myostatin was downregulated at 20 nM treatment (p = 0.03) and showed a trend towards downregulation at 10 nM myostatin (p = 0.06). (C)—miR-495-3p expression in VSMCs treated with 10 and 20 nM myostatin was decreased with more than 80% by both treatment concentrations (p = 0.0098 and p = 0.0088, respectively). Mean expression is shown and error bar represents SEM (n = 3). One-sample t-test performed with 100% of control expression as hypothetical value. * p < 0.05, ** p < 0.01.