Figure 2.

Selected cytokines during treatment with belimumab. The charts illustrate serum levels of selected cytokines—interferon (IFN)-α2, interleukin (IL)-6, IL-10, and IL-17A—at specific time points during treatment with belimumab. The blue lines connect mean values of the distributions at the different times points, and the whiskers represent standard errors of the mean. The numbers of patients contributing to the measurements are indicated. Asterisks indicate statistically significant changes compared with baseline, on the basis of the non-parametric paired Wilcoxon signed rank test.