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Schematic of PHLD class proteins and phylogenetic tree adopted from constraint-based alignment tool (COBALT, NIH). PHD (Pleckstrin Homology Domain); PolyQ (Polyglutamine); PQ (Proline Glutamine Repeat); PH (Proline Histidine Repeat); AA (Alanine Repeats); FHA (Forkhead-associated Domain); CC (Coiled-coil Domain).
